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KMID : 0882420170920040406
Korean Journal of Medicine
2017 Volume.92 No. 4 p.406 ~ p.410
Inflammatory Pseudotumor of the Spleen Associated with Autoimmune Thyroiditis
Ryu Je-Hyun

Lee Kyung-Hae
Kim Jae-Hyun
Park Sun-Man
Kim Young-Jin
Kae Sea-Hyub
Lee Jin
Abstract
Inflammatory pseudotumor is a benign disease entity, which is histologically composed of inflammatory cells and fibrotic stroma. It is mainly found in the respiratory tract, but it has also been reported in the liver, central nervous system, soft tissues, urological system, and gastrointestinal tract. It is extremely rare in the spleen and there have been no cases of splenic inflammatory pseudotumor associated with autoimmune thyroiditis in Korea. The pathogenesis or etiology is unknown, but hypotheses include infection, autoimmunity, and parenchymal necrosis with hemorrhage. Because inflammatory pseudotumor may mimic malignant tumors on radiologic findings, pathologic confirmation is necessary to distinguish it from lymphoproliferative disorders of the spleen and other malignant tumors. We report a case of inflammatory pseudotumor of the spleen associated with autoimmune thyroiditis in a patient who complained of periumbilical pain.
KEYWORD
Inflammatory pseudotumor, Spleen, Thyroiditis, Autoimmune
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